Karen's Replicator

http://www.karenware.com/powertools/ptreplicator.asp

Automatically backup files, directories, even entire drives! Karen's
Replicator copies selected files from one drive/folder to another.

Source and Destination folders can reside anywhere on your network.
Files larger than 2 GB are supported.

Options include repeated copies at intervals as short as a few minutes,
or as long as several months, copy only files that have changed, and
the replication of file deletions.

New features allow you to specify which files should not be copied, and
also which days a file should be skipped!